GABA calls stop in the striatum
نویسندگان
چکیده
منابع مشابه
Analysis of gaba and glutamate in the mouse dorsal striatum
................................................................................................87 Autobiographical Statement...................................................................89
متن کاملArkypallidal Cells Send a Stop Signal to Striatum
The suppression of inappropriate actions is critical for flexible behavior. Cortical-basal ganglia networks provide key gating mechanisms for action suppression, yet the specific roles of neuronal subpopulations are poorly understood. Here, we examine Arkypallidal (‘‘Arky’’) and Prototypical (‘‘Proto’’) globus pallidus neurons during a Stop task, which requires abrupt cancellation of an imminen...
متن کاملThe Effects of Mild Forced Treadmill Exercise and GABA-B Agonist on Locomotor Activity and Anxiety-Behavior in Rats with Striatum Dysfunction
Background. the basal ganglia’s circuit dysfunction has a major role in a range of movement disorders. Some evidence has shown that exercise can improve performance, especially locomotor activity after brain injuries. There was currently insufficient information to define the impacts of intensity, duration, and frequency of different exercises. Objectives. in this study, we examine the r...
متن کاملEstradiol attenuates the K+-induced increase in extracellular GABA in rat striatum.
Estradiol acts rapidly and directly to inhibit L-type Ca2+ current in medium spiny neurons from striatum. Since medium spiny neurons contain gamma-aminobutyric acid (GABA), we hypothesized that estradiol inhibition of Ca2+ channel current in the cell body would result in decreased GABA release. In this study, we examined the effect of estradiol on the concentration of GABA, taurine, and glutama...
متن کاملFeedforward inhibition of projection neurons by fast-spiking GABA interneurons in the rat striatum in vivo.
Discharge activities and local field potentials were recorded in the orofacial motor cortex and in the corresponding rostrolateral striatum of urethane-anesthetized rats. Striatal projection neurons were identified by antidromic activation and fast-spiking GABAergic interneurons (FSIs) by their unique characteristics: briefer spike and burst responses. Juxtacellular injection of neurobiotin com...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2012
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn3382